877468-30-9
877468-30-9 structure
- Name: Anti-inflammatory agent 42
- Chemical Name: WAY-620520
- CAS Number: 877468-30-9
- Molecular Formula: C20H12N2OS
- Molecular Weight: 328.39
- Catalog: Signaling Pathways Immunology/Inflammation Interleukin Related
- Create Date: 2022-12-05 10:53:28
- Modify Date: 2024-04-03 17:19:38
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Anti-inflammatory agent 42 (Compound 10j) is an anti-inflammatory agent. Anti-inflammatory agent 42 shows excellent inhibition on the expression of TNF-α and IL-6 in LPS (HY-D1056)-stimulated macrophages[1].
| Name | WAY-620520 |
|---|---|
| Synonyms |
2-Naphthalen-1-ylmethylene-benzo[4,5]imidazo[2,1-b]thiazol-3-one
Thiazolo[3,2-a]benzimidazol-3(2H)-one, 2-(1-naphthylmethylene)- (2Z)-2-(1-Naphthylmethylene)[1,3]thiazolo[3,2-a]benzimidazol-3(2H)-one Thiazolo[3,2-a]benzimidazol-3(2H)-one, 2-(1-naphthalenylmethylene)-, (2Z)- |
| Description | Anti-inflammatory agent 42 (Compound 10j) is an anti-inflammatory agent. Anti-inflammatory agent 42 shows excellent inhibition on the expression of TNF-α and IL-6 in LPS (HY-D1056)-stimulated macrophages[1]. |
|---|---|
| Related Catalog | |
| In Vitro | Anti-inflammatory agent 42 (Compound 10j; 10 μM; 2 h) 抑制 LPS 诱导的 RAW 264.7 巨噬细胞 TNF-α 和 IL-6 分泌[1]。 |
| References |
| Density | 1.4±0.1 g/cm3 |
|---|---|
| Boiling Point | 579.8±53.0 °C at 760 mmHg |
| Melting Point | 213-215 °C(Solv: acetic acid (64-19-7)) |
| Molecular Formula | C20H12N2OS |
| Molecular Weight | 328.39 |
| Flash Point | 304.5±30.9 °C |
| Exact Mass | 328.067047 |
| LogP | 6.16 |
| Vapour Pressure | 0.0±1.6 mmHg at 25°C |
| Index of Refraction | 1.752 |