106061-19-2
106061-19-2 structure
- Name: GnRH Associated Peptide (25-53), human
- Chemical Name: GnRH Associated Peptide (25-53), human
- CAS Number: 106061-19-2
- Molecular Formula: C140H226N40O49S
- Molecular Weight: 3285.60
- Catalog: Signaling Pathways GPCR/G Protein GNRH Receptor
- Create Date: 2022-12-02 18:48:15
- Modify Date: 2024-04-05 18:23:01
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GnRH Associated Peptide (GAP) (25-53), human is the human gonadotropin-releasing hormone-associated peptide (GAP) 25-53 fragment (hGAP-25-53), can be used as immunogen to generate antiseras including MC-1, MC-2, and MC-3. GAP is joined to the luteinizing hormone-releasing hormone (LH-RH) sequence by a 3 amino acid processing site[1].
| Name | GnRH Associated Peptide (25-53), human |
|---|
| Description | GnRH Associated Peptide (GAP) (25-53), human is the human gonadotropin-releasing hormone-associated peptide (GAP) 25-53 fragment (hGAP-25-53), can be used as immunogen to generate antiseras including MC-1, MC-2, and MC-3. GAP is joined to the luteinizing hormone-releasing hormone (LH-RH) sequence by a 3 amino acid processing site[1]. |
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| Related Catalog | |
| In Vitro | GAP (10 nM; 4 h) stimulates the release of both gonadotropins in anterior pituitaries from female Sprague-Dawley rats, but inhibits the basal secretion of prolactin by ~50%, compared with inhibition levels reported for dopamin, a known prolactin-inhibiting factor[2]. GAP (0.1-10 nM; 3-4 h) inhibits prolactin secretion by 40-45%, with an IC50 value of 0.25 nM[2]. |
| Molecular Formula | C140H226N40O49S |
|---|---|
| Molecular Weight | 3285.60 |