2819989-67-6
2819989-67-6 structure
- Name: PBRM1-BD2-IN-6
- Chemical Name: PBRM1-BD2-IN-6
- CAS Number: 2819989-67-6
- Molecular Formula: C16H15ClN2O
- Molecular Weight: 286.76
- Catalog: Signaling Pathways Epigenetics Epigenetic Reader Domain
- Create Date: 2022-11-30 11:23:08
- Modify Date: 2024-04-05 20:41:15
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PBRM1-BD2-IN-6 is a potent PBRM1 bromodomain inhibitor with an IC50 value of 0.22 µM. PBRM1-BD2-IN-6 shows antiproliferation activity. PBRM1-BD2-IN-6 has the potential for the research of PBRM1-dependent cancer[1].
| Name | PBRM1-BD2-IN-6 |
|---|
| Description | PBRM1-BD2-IN-6 is a potent PBRM1 bromodomain inhibitor with an IC50 value of 0.22 µM. PBRM1-BD2-IN-6 shows antiproliferation activity. PBRM1-BD2-IN-6 has the potential for the research of PBRM1-dependent cancer[1]. |
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| Related Catalog | |
| Target |
IC50: 0.22 nM (PBRM1-BD2)[1] |
| In Vitro | PBRM1-BD2-IN-6 (compound 25) (0.1, 1, 10 μM; 5 days) shows antiproliferation activity with IC50 values of 0.66, 0.77, 0.32 µM for LNCaP, PC3, HEK293T cells, respectively[1]. Cell Proliferation Assay[1] Cell Line: LNCaP, PC3, HEK293T cells Concentration: 0.1, 1, 10 μM Incubation Time: 5 days Result: Inhibited the cell growth with IC50 values of 0.66, 0.77, 0.32 µM for LNCaP, PC3, HEK293T cells, respectively. |
| Molecular Formula | C16H15ClN2O |
|---|---|
| Molecular Weight | 286.76 |