2797225-47-7

2797225-47-7 structure
2797225-47-7 structure
  • Name: PfGSK3/PfPK6-IN-2
  • Chemical Name: PfGSK3/PfPK6-IN-2
  • CAS Number: 2797225-47-7
  • Molecular Formula: C24H25Cl2N5OS
  • Molecular Weight: 502.46
  • Catalog: Signaling Pathways PI3K/Akt/mTOR GSK-3
  • Create Date: 2022-11-21 19:56:22
  • Modify Date: 2025-08-22 02:57:36
  • PfGSK3/PfPK6-IN-2 is a potent dual PfGSK3/PfPK6 (Plasmodium falciparum GSK3/PK6) inhibitor (IC50: 172 nM and 11 nM respectively). PfGSK3/PfPK6-IN-2 can be used in the research of Malaria[1].

Name PfGSK3/PfPK6-IN-2
Description PfGSK3/PfPK6-IN-2 is a potent dual PfGSK3/PfPK6 (Plasmodium falciparum GSK3/PK6) inhibitor (IC50: 172 nM and 11 nM respectively). PfGSK3/PfPK6-IN-2 can be used in the research of Malaria[1].
Related Catalog
Target

Plasmodium falciparum GSK3/PK6 (PfGSK3/PfPK6)[1]

In Vitro PfGSK3/PfPK6-IN-2 (compound 23d) inhibits P. falciparum 3D7 load in erythrocytes (EC50: 552 nM)[1]. PfGSK3/PfPK6-IN-2 (2 μM) shows cytotoxicity against HepG2 cells[1].
Molecular Formula C24H25Cl2N5OS
Molecular Weight 502.46
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