1274611-43-6

1274611-43-6 structure

Name: Antibacterial agent 125
Chemical Name: Antibacterial agent 125
CAS Number: 1274611-43-6
Molecular Formula: C₁₅H₁₁ClN₂O
Molecular Weight: 270.71
Catalog: Signaling Pathways Anti-infection Bacterial
Create Date: 2023-01-29 21:01:27
Modify Date: 2024-01-12 19:45:04
Antibacterial agent 125 is an antibacterial agent. Antibacterial agent 125 has a potent antimicrobial activity against clinically relevant Gram-positive pathogens with MIC50 values range from 0.25 - 8 μM. Antibacterial agent 125 can be used for the research of antimicrobial resistance[1].

Name	Antibacterial agent 125

Description	Antibacterial agent 125 is an antibacterial agent. Antibacterial agent 125 has a potent antimicrobial activity against clinically relevant Gram-positive pathogens with MIC50 values range from 0.25 - 8 μM. Antibacterial agent 125 can be used for the research of antimicrobial resistance[1].
Related Catalog	Research Areas >> Infection Research Areas >> Inflammation/Immunology Signaling Pathways >> Anti-infection >> Bacterial
Target	MIC50: 0.25 - 8 μM (Gram-positive pathogens)[1]
In Vitro	Antibacterial agent 125 对临床相关的革兰氏阳性病原体具有活性，MIC50 值为 0.25-8 μM[1]。 Antibacterial agent 125 对耐甲氧西林 Staphylococcus aureus strain 菌株具有抑制活性，且在人体细胞中未表现出细胞毒性[1]。 Antibacterial agent 125 具有高代谢稳定性和优异的安全性[1]。 Antibacterial agent 125 传代 10 次后不产生耐药性，具有中度抑制生物膜形成的能力[1]。
References	[1]. Francesca Brunelli, et al. Isocyanides in med chem: A scaffold hopping approach for the identification of novel 4-isocyanophenylamides as potent antibacterial agents against methicillin-resistant Staphylococcusaureus. Eur J Med Chem. 2022 Nov 26;246:114950.

Molecular Formula	C₁₅H₁₁ClN₂O
Molecular Weight	270.71