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2618700-77-7

2618700-77-7 structure
2618700-77-7 structure
  • Name: Artemisiane E
  • Chemical Name: Artemisiane E
  • CAS Number: 2618700-77-7
  • Molecular Formula: C20H22O5
  • Molecular Weight: 342.39
  • Catalog: Signaling Pathways PI3K/Akt/mTOR Akt
  • Create Date: 2023-03-03 12:34:22
  • Modify Date: 2024-04-03 19:17:32
  • Artemisiane E (Compound 8) is a potent PI3K/AKT pathway inhibitor with an IC50 of 8.9 μM[1].
Name Artemisiane E
Description Artemisiane E (Compound 8) is a potent PI3K/AKT pathway inhibitor with an IC50 of 8.9 μM[1].
Related Catalog
Target

IC50: 8.9 μM (PI3K/AKT pathway)[1]

In Vitro Artemisiane E (Compound 8) (25 and 50 μM) inhibits AKT activity in MM121224 cells[1].
References

[1]. Dürr L, et al. A Dimerosesquiterpene and Sesquiterpene Lactones from Artemisia argyi Inhibiting Oncogenic PI3K/AKT Signaling in Melanoma Cells. J Nat Prod. 2022 Nov 25;85(11):2557-2569.  

Molecular Formula C20H22O5
Molecular Weight 342.39

Chemsrc provides CAS#:2618700-77-7 MSDS, density, melting point, boiling point, structure, formula, molecular weight, synthetic route, etc.
title: CAS No. 2618700-77-7 | Chemsrc address: https://m.chemsrc.com/en/baike/1727195.html

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