Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Avizakimab (anti-IL-21)
Price: Check
Purity: 95.0%
Stocking Period: 10 Day
Contact: Yang
Email: sales@echemcloud.com

2229685-51-0

2229685-51-0 structure

2229685-51-0 structure

Name: Avizakimab
Chemical Name: Avizakimab
CAS Number: 2229685-51-0
Molecular Formula:
Molecular Weight:
Catalog: Signaling Pathways Immunology/Inflammation Interleukin Related
Create Date: 2023-01-11 18:22:39
Modify Date: 2024-04-06 17:54:21
Avizakimab (BOS161721) is a humanized IgG1 monoclonal antibody that targets interleukin-21[1].

Name	Avizakimab

Description	Avizakimab (BOS161721) is a humanized IgG1 monoclonal antibody that targets interleukin-21[1].
Related Catalog	Signaling Pathways >> Immunology/Inflammation >> Interleukin Related Research Areas >> Inflammation/Immunology
In Vitro	Avizakimab (BOS161721) 可阻止 IL-21 与 IL-21 受体 (IL-21R) 结合，并抑制生物活性[1]。 Avizakimab 可抑制 IL-21 诱导的下游信号传导、浆细胞分化和自然杀伤细胞激活，并抑制抗体对匙孔戚血蓝蛋白 (keyhole limpet hemocyanin; KLH) 抗原的反应[1]。
References	[1]. Hussaini A, et al. A Double-Blind, Phase I, Single Ascending Dose Study to Assess the Safety, Pharmacokinetics, and Pharmacodynamics of BOS161721 in Healthy Subjects. Clin Transl Sci. 2020 Mar;13(2):337-344.

No Any Chemical & Physical Properties

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