2230520-62-2

2230520-62-2 structure

Name: β2AR/M-receptor agonist-1
Chemical Name: β2AR/M-receptor agonist-1
CAS Number: 2230520-62-2
Molecular Formula: C₄₃H₅₆BrN₃O₇
Molecular Weight: 806.82
Catalog: Signaling Pathways GPCR/G Protein Adrenergic Receptor
Create Date: 2023-01-15 13:27:04
Modify Date: 2024-01-12 17:24:04
β2AR/M-receptor agonist-1 (example 131) is a muscarinic antagonist and β2 adrenoceptor agonist (MABA). β2AR/M-receptor agonist-1 shows potency to β2 adrenoceptor with an EC50 value of 9.2 nM. β2AR/M-receptor agonist-1 also has potency to muscarinic receptor with a Ki value of 30.2 nM. β2AR/M-receptor agonist-1 shows MABA potency with an EC50 value of 4.0 nM[1].

Name	β2AR/M-receptor agonist-1

Description	β2AR/M-receptor agonist-1 (example 131) is a muscarinic antagonist and β2 adrenoceptor agonist (MABA). β2AR/M-receptor agonist-1 shows potency to β2 adrenoceptor with an EC50 value of 9.2 nM. β2AR/M-receptor agonist-1 also has potency to muscarinic receptor with a Ki value of 30.2 nM. β2AR/M-receptor agonist-1 shows MABA potency with an EC50 value of 4.0 nM[1].
Related Catalog	Signaling Pathways >> Neuronal Signaling >> mAChR Research Areas >> Cardiovascular Disease Signaling Pathways >> GPCR/G Protein >> mAChR Signaling Pathways >> GPCR/G Protein >> Adrenergic Receptor
In Vivo	β2AR/M-receptor agonist-1 (0.01 和 0.1 mg/kg；静脉注射，一次) 降低比格犬的心率[1]。
References	[1]. WEN SHOUMING, et al. CLASS OF BIFUNCTIONAL COMPOUNDS WITH QUATERNARY AMMONIUM SALT STRUCTURE. WO2018108089. 2018.

Molecular Formula	C₄₃H₅₆BrN₃O₇
Molecular Weight	806.82