2173014-90-7
2173014-90-7 structure
- Name: cis-1-fluoro-4-OTBS-cyclohexane
- Chemical Name: cis-1-fluoro-4-OTBS-cyclohexane
- CAS Number: 2173014-90-7
- Molecular Formula: C12H25FOSi
- Molecular Weight: 232.41
- Create Date: 2023-01-29 11:29:36
- Modify Date: 2023-01-29 11:29:36
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Description The incorporation of fluorine in agrochemical and pharmaceutical compounds is of high interest due to the ability to fine-tune the polarity, pKA-value, conformation and metabolic stability. Derived from acis-selective hydrogenation developed by Glorius and coworkers, this fluorinated compound displays a diverse utility as a building block for chemical synthesis. Fluoro-cyclohexanol allows for the straightforward application in organic synthesis, after simple deprotection. It can be utilized to prepare fluorinated analogues of known compounds.
| Name | cis-1-fluoro-4-OTBS-cyclohexane |
|---|---|
| Synonyms |
Cyclohexane, 1-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-4-fluoro-, cis-
[(cis-4-Fluorocyclohexyl)oxy](dimethyl)(2-methyl-2-propanyl)silane |
| Density | 0.9±0.1 g/cm3 |
|---|---|
| Boiling Point | 234.0±33.0 °C at 760 mmHg |
| Molecular Formula | C12H25FOSi |
| Molecular Weight | 232.41 |
| Flash Point | 95.3±25.4 °C |
| Exact Mass | 232.165863 |
| LogP | 4.32 |
| Vapour Pressure | 0.1±0.4 mmHg at 25°C |
| Index of Refraction | 1.428 |