851960-68-4
851960-68-4 structure
- Name: H-L-Photo-methionine HCl
- Chemical Name: H-L-Photo-methionine HCl
- CAS Number: 851960-68-4
- Molecular Formula: C6H11N3O2
- Molecular Weight: 193.63
- Create Date: 2023-01-16 06:31:20
- Modify Date: 2025-09-04 18:08:28
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Description H-L-Photo-Methionine HCl is a diazirine-containingmethionine amino acid and multifunctional photo-crosslinker. Its incorporation into peptides or small-molecule probes and tools allows for photoaffinity labeling of cellular targets and protein-protein interactions upon UV light (~360 nm) irradiation to form a covalent bond. This and othermultifunctional probe building blockswill continue to accelerate drug discovery research for probing cellular mechanisms, target ID/validation, and understanding traditionally undruggable targets. An Fmoc-protected version is also available as907367.
| Name | H-L-Photo-methionine HCl |
|---|---|
| Synonyms | Photo-crosslinking amino acid, (S)-2-Amino-4-(3-methyl-3H-diazirin-3-yl)butanoic acid hydrochloride, Photoprobe building block, (S)-2-Amino-4-(3H-diazirin-3-yl)pentanoic acid hydrochloride, Photo-Met, Diazirine amino acid |
| Density | 1.48±0.1 g/cm3(Predicted) |
|---|---|
| Boiling Point | 280.3±46.0 °C(Predicted) |
| Molecular Formula | C6H11N3O2 |
| Molecular Weight | 193.63 |
| Flash Point | 123.3±29.0 °C |
| Exact Mass | 157.085129 |
| LogP | 0.34 |
| Vapour Pressure | 0.0±1.2 mmHg at 25°C |
| Index of Refraction | 1.632 |