2874263-74-6

2874263-74-6 structure

Name: Antituberculosis agent-8
Chemical Name: Antituberculosis agent-8
CAS Number: 2874263-74-6
Molecular Formula: C₂₅H₁₉F₃N₂O₃
Molecular Weight: 452.43
Catalog: Signaling Pathways Anti-infection Bacterial
Create Date: 2023-02-02 17:36:19
Modify Date: 2025-08-26 16:58:59
Antituberculosis agent-8 (Compound 9i) is an antitubercular agent with an MIC of 3.53 μM (1.6 μg/mL) against M. tuberculosis H37Rv. Antituberculosis agent-8 also shows good antifungal activity against A. niger with an MIC of 62.50 μM[1].

Name	Antituberculosis agent-8

Description	Antituberculosis agent-8 (Compound 9i) is an antitubercular agent with an MIC of 3.53 μM (1.6 μg/mL) against M. tuberculosis H37Rv. Antituberculosis agent-8 also shows good antifungal activity against A. niger with an MIC of 62.50 μM[1].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Anti-infection >> Fungal Signaling Pathways >> Anti-infection >> Bacterial
In Vitro	Antituberculosis agent-8 (Compound 9i) shows antimicrobial activity with MICs of 3.53, 62.50, 125, 250 and 250 μM against M. tuberculosis H37Rv, A. Niger, C. albicans, S. albus, B. subtilis, respectively[1].
References	[1]. Shinde A, et al. Synthesis, Characterization, and Antimicrobial Activity Screening of Some Novel 3-(2-(3-(Substituted benzyloxy)oxetan-3-yl)-3-fluorophenoxy)-8-fluoro-2-methylquinoline Derivatives as Potential Antimycobacterial Agents. ACS Omega. 2022 Dec 6;7(50):47096-47107.

Molecular Formula	C₂₅H₁₉F₃N₂O₃
Molecular Weight	452.43