Antituberculosis agent-8

Modify Date: 2025-08-26 16:58:59

Antituberculosis agent-8 Structure
Antituberculosis agent-8 structure
 Common Name Antituberculosis agent-8
CAS Number 2874263-74-6 Molecular Weight 452.43
Density N/A Boiling Point N/A
Molecular Formula C25H19F3N2O3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Antituberculosis agent-8


Antituberculosis agent-8 (Compound 9i) is an antitubercular agent with an MIC of 3.53 μM (1.6 μg/mL) against M. tuberculosis H37Rv. Antituberculosis agent-8 also shows good antifungal activity against A. niger with an MIC of 62.50 μM[1].

 Names

Name Antituberculosis agent-8

 Antituberculosis agent-8 Biological Activity

Description Antituberculosis agent-8 (Compound 9i) is an antitubercular agent with an MIC of 3.53 μM (1.6 μg/mL) against M. tuberculosis H37Rv. Antituberculosis agent-8 also shows good antifungal activity against A. niger with an MIC of 62.50 μM[1].
Related Catalog
In Vitro Antituberculosis agent-8 (Compound 9i) shows antimicrobial activity with MICs of 3.53, 62.50, 125, 250 and 250 μM against M. tuberculosis H37Rv, A. Niger, C. albicans, S. albus, B. subtilis, respectively[1].
References

[1]. Shinde A, et al. Synthesis, Characterization, and Antimicrobial Activity Screening of Some Novel 3-(2-(3-(Substituted benzyloxy)oxetan-3-yl)-3-fluorophenoxy)-8-fluoro-2-methylquinoline Derivatives as Potential Antimycobacterial Agents. ACS Omega. 2022 Dec 6;7(50):47096-47107.  

 Chemical & Physical Properties

Molecular Formula C25H19F3N2O3
Molecular Weight 452.43
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