2719691-01-5

2719691-01-5 structure
2719691-01-5 structure
  • Name: AZ-5104-d2
  • Chemical Name: AZ-5104-d2
  • CAS Number: 2719691-01-5
  • Molecular Formula: C27H29D2N7O2
  • Molecular Weight: 487.59
  • Catalog: Signaling Pathways JAK/STAT Signaling EGFR
  • Create Date: 2023-03-05 20:24:51
  • Modify Date: 2024-04-05 18:49:44
  • AZ-5104-d2 is the deuterium labeled AZ-5104. AZ-5104 is an EGFR inhibitor with IC50s of 1 nM, 6 nM, 1 nM, 25 nM and 7 nM for EGFRL858R/T790M, EGFRL858R, EGFRL861Q, EGFR and ErbB4, respectively[1].

Name AZ-5104-d2
Description AZ-5104-d2 is the deuterium labeled AZ-5104. AZ-5104 is an EGFR inhibitor with IC50s of 1 nM, 6 nM, 1 nM, 25 nM and 7 nM for EGFRL858R/T790M, EGFRL858R, EGFRL861Q, EGFR and ErbB4, respectively[1].
Related Catalog
References

[1]. Cross DA, et al. AZD9291, an irreversible EGFR TKI, overcomes T790M-mediated resistance to EGFR inhibitors in lung cancer. Cancer Discov. 2014 Sep;4(9):1046-61.  

Molecular Formula C27H29D2N7O2
Molecular Weight 487.59
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