1987854-08-9
1987854-08-9 structure
- Name: Bersanlimab
- Chemical Name: Bersanlimab
- CAS Number: 1987854-08-9
- Molecular Formula:
- Molecular Weight:
- Catalog: Signaling Pathways Cytoskeleton Integrin
- Create Date: 2023-01-30 17:36:33
- Modify Date: 2024-02-06 10:04:36
-
Bersanlimab (BI-505) is a fully human monoclonal antibody that targets intercellular adhesion molecule-1 (ICAM-1 or CD54). Bersanlimab has anticancer effects[1].
| Name | Bersanlimab |
|---|
| Description | Bersanlimab (BI-505) is a fully human monoclonal antibody that targets intercellular adhesion molecule-1 (ICAM-1 or CD54). Bersanlimab has anticancer effects[1]. |
|---|---|
| Related Catalog | |
| In Vitro | BI-505（1 ng/mL-1000 μg/mL）剂量依赖性地诱导表达 ICAM-1 的 Ramos、Raji 和 Daudi 淋巴瘤细胞的程序性细胞死亡 (PCD)[1]。 |
| In Vivo | Bersanlimab（BI-505；20 mg/kg；腹腔注射；每周两次；持续 21 天）显着减少肿瘤生长并延长动物存活期[1]。 Animal Model: SCID mice injected with ARH-77 cells[1] Dosage: 20 mg/kg Administration: i.p.; twice-weekly; for 21 days Result: Significantly reduced tumor growth and prolonged animal survival. |
| References |
| No Any Chemical & Physical Properties |