762242-59-1

762242-59-1 structure

Name: Clathrin-IN-4
Chemical Name: Clathrin-IN-4
CAS Number: 762242-59-1
Molecular Formula: C₁₇H₁₈Br₂N₂O
Molecular Weight: 426.15
Catalog: Signaling Pathways Cytoskeleton Dynamin
Create Date: 2023-03-06 10:28:46
Modify Date: 2024-09-18 16:08:25
Clathrin-IN-4 (compound 8b), a Wiskostatin (HY-12534) analogue, is a potent inhibitor of clathrin mediated endocytosis with an IC50 of 2.1 μM. Clathrin-IN-4 is a dynamin I GTPase activity inhibitor with an IC50 of 9.1 μM[1].

Name	Clathrin-IN-4

Description	Clathrin-IN-4 (compound 8b), a Wiskostatin (HY-12534) analogue, is a potent inhibitor of clathrin mediated endocytosis with an IC50 of 2.1 μM. Clathrin-IN-4 is a dynamin I GTPase activity inhibitor with an IC50 of 9.1 μM[1].
Related Catalog	Research Areas >> Neurological Disease Signaling Pathways >> Cytoskeleton >> Dynamin
References	[1]. Peter J Cossar, et al. Wiskostatin and other carbazole scaffolds as off target inhibitors of dynamin I GTPase activity and endocytosis. Eur J Med Chem. 2022 Dec 15;247:115001.

Molecular Formula	C₁₇H₁₈Br₂N₂O
Molecular Weight	426.15