Clathrin-IN-4

Modify Date: 2025-08-27 00:26:44

Clathrin-IN-4 structure	Common Name	Clathrin-IN-4
	CAS Number	762242-59-1	Molecular Weight	426.15
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₇H₁₈Br₂N₂O	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Clathrin-IN-4

Clathrin-IN-4 (compound 8b), a Wiskostatin (HY-12534) analogue, is a potent inhibitor of clathrin mediated endocytosis with an IC50 of 2.1 μM. Clathrin-IN-4 is a dynamin I GTPase activity inhibitor with an IC50 of 9.1 μM[1].

Name	Clathrin-IN-4

Description	Clathrin-IN-4 (compound 8b), a Wiskostatin (HY-12534) analogue, is a potent inhibitor of clathrin mediated endocytosis with an IC50 of 2.1 μM. Clathrin-IN-4 is a dynamin I GTPase activity inhibitor with an IC50 of 9.1 μM[1].
Related Catalog	Research Areas >> Neurological Disease Signaling Pathways >> Cytoskeleton >> Dynamin
References	[1]. Peter J Cossar, et al. Wiskostatin and other carbazole scaffolds as off target inhibitors of dynamin I GTPase activity and endocytosis. Eur J Med Chem. 2022 Dec 15;247:115001.

Molecular Formula	C₁₇H₁₈Br₂N₂O
Molecular Weight	426.15

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Clathrin-IN-4

Use of Clathrin-IN-4

Names

Clathrin-IN-4 Biological Activity

Chemical & Physical Properties

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.