1776055-29-8

1776055-29-8 structure

Name: Efflux inhibitor-1
Chemical Name: Efflux inhibitor-1
CAS Number: 1776055-29-8
Molecular Formula: C₂₈H₂₅N₅O₃
Molecular Weight: 479.53
Catalog: Signaling Pathways Membrane Transporter/Ion Channel BCRP
Create Date: 2023-01-29 12:00:17
Modify Date: 2024-04-05 18:46:14
Efflux inhibitor-1 (compound 2) is a pyrazolo[1,5-a]pyrimidine efflux inhibitor. Efflux inhibitor-1 selectively targets toward ABCG2/BCRP over ABCB1 with IC50s of 0.45 μM and 2.17 μM, respectively[1].

Name	Efflux inhibitor-1

Description	Efflux inhibitor-1 (compound 2) is a pyrazolo[1,5-a]pyrimidine efflux inhibitor. Efflux inhibitor-1 selectively targets toward ABCG2/BCRP over ABCB1 with IC50s of 0.45 μM and 2.17 μM, respectively[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Membrane Transporter/Ion Channel >> BCRP
Target	IC50: 0.45 μM (ABCG2/BCRP), 2.17 μM (ABCB1)[1]
References	[1]. Larson, et al. Selective efflux inhibitors and related pharmaceutical compositions and methods of treatment: United States, US9056111[P]. 2015-06-16.

Molecular Formula	C₂₈H₂₅N₅O₃
Molecular Weight	479.53