Efflux inhibitor-1

Modify Date: 2024-04-05 18:46:14

Efflux inhibitor-1 structure	Common Name	Efflux inhibitor-1
	CAS Number	1776055-29-8	Molecular Weight	479.53
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₈H₂₅N₅O₃	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Efflux inhibitor-1

Efflux inhibitor-1 (compound 2) is a pyrazolo[1,5-a]pyrimidine efflux inhibitor. Efflux inhibitor-1 selectively targets toward ABCG2/BCRP over ABCB1 with IC50s of 0.45 μM and 2.17 μM, respectively[1].

Name	Efflux inhibitor-1

Description	Efflux inhibitor-1 (compound 2) is a pyrazolo[1,5-a]pyrimidine efflux inhibitor. Efflux inhibitor-1 selectively targets toward ABCG2/BCRP over ABCB1 with IC50s of 0.45 μM and 2.17 μM, respectively[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Membrane Transporter/Ion Channel >> BCRP
Target	IC50: 0.45 μM (ABCG2/BCRP), 2.17 μM (ABCB1)[1]
References	[1]. Larson, et al. Selective efflux inhibitors and related pharmaceutical compositions and methods of treatment: United States, US9056111[P]. 2015-06-16.

Molecular Formula	C₂₈H₂₅N₅O₃
Molecular Weight	479.53

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Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Efflux inhibitor-1
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Purity: 98.0%
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The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.