2097125-54-5
2097125-54-5 structure
- Name: Garetosmab
- Chemical Name: Garetosmab
- CAS Number: 2097125-54-5
- Molecular Formula:
- Molecular Weight:
- Catalog: Research Areas Inflammation/Immunology
- Create Date: 2023-04-09 09:00:18
- Modify Date: 2024-01-10 10:02:46
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Garetosmab (REGN 2477) is a fully human IgG4 monoclonal antibody that specifically inhibits activin A. Garetosmab can be used for fibrodysplasia ossificans progressiva (FOP) research[1].
| Name | Garetosmab |
|---|
| Description | Garetosmab (REGN 2477) is a fully human IgG4 monoclonal antibody that specifically inhibits activin A. Garetosmab can be used for fibrodysplasia ossificans progressiva (FOP) research[1]. |
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| Related Catalog | |
| In Vitro | Garetosmab (REGN 2477) specifically binds to and blocks signaling of activin proteins containing the inhibin βα subunit (activins A, AB, and AC). In vitro, Garetosmab has high affinity and specificity for activins A, AB, and AC, but does not bind or functionally inhibit other TGF-β family ligands that share the same activin receptor pathways, including activin B, inhibin A, BMP-2, BMP6, BMP9, BMP10, GDF8, and GDF11[1]. |
| References |
| No Any Chemical & Physical Properties |