2873418-48-3

2873418-48-3 structure
2873418-48-3 structure
  • Name: Tyrosinase-IN-10
  • Chemical Name: Tyrosinase-IN-10
  • CAS Number: 2873418-48-3
  • Molecular Formula: C16H12O4
  • Molecular Weight: 268.26
  • Catalog: Signaling Pathways Metabolic Enzyme/Protease Tyrosinase
  • Create Date: 2023-01-26 19:13:52
  • Modify Date: 2024-04-06 19:23:23
  • Tyrosinase-IN-10 (Compound 23) is a partially competitive tyrosinase inhibitor with an IC50 of 1.6 μM against tyrosinase activity from human melanoma cell lysates[1].

Name Tyrosinase-IN-10
Description Tyrosinase-IN-10 (Compound 23) is a partially competitive tyrosinase inhibitor with an IC50 of 1.6 μM against tyrosinase activity from human melanoma cell lysates[1].
Related Catalog
Target

IC50: 1.6 μM (human tyrosinase)[1]

In Vitro Tyrosinase-IN-10 (Compound 23) (0-100 μM; 96 h) 抑制 MNT-1 全细胞黑素生成,IC50 为 29 μM, 对 MNT-1 的细胞毒性 CC50 为 91 μM[1]。 Cell Cytotoxicity Assay[1] Cell Line: MNT-1 cells Concentration: 0-100 μM Incubation Time: 96 h Result: Showed cytotoxicity with a CC50 of 91 μM.
References

[1]. Roulier B, et al. Resorcinol-based hemiindigoid derivatives as human tyrosinase inhibitors and melanogenesis suppressors in human melanoma cells. Eur J Med Chem. 2023 Jan 15;246:114972.  

Molecular Formula C16H12O4
Molecular Weight 268.26
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