2154342-17-1
2154342-17-1 structure
- Name: Thalidomide-4-NH-PEG1-NH-Boc
- Chemical Name: Thalidomide-NH-PEG1-NH-Boc
- CAS Number: 2154342-17-1
- Molecular Formula: C22H28N4O7
- Molecular Weight: 460.48
- Catalog: Signaling Pathways PROTAC Ligand for E3 Ligase
- Create Date: 2023-02-27 18:07:39
- Modify Date: 2025-08-25 16:06:11
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Thalidomide-4-NH-PEG1-NH-Boc is a Boc-modified Thalidomide (HY-14658) that acts as a Cereblon ligand to recruit CRBN protein. The Boc protecting group at the end of Thalidomide-4-NH-PEG1-NH-Boc can be removed under acidic conditions to participate in the synthesis of PROTAC molecules. Thalidomide-4-NH-PEG1-NH-Boc is a key intermediate in the synthesis of CRBN-based PROTAC molecules.
| Name | Thalidomide-NH-PEG1-NH-Boc |
|---|
| Description | Thalidomide-4-NH-PEG1-NH-Boc is a Boc-modified Thalidomide (HY-14658) that acts as a Cereblon ligand to recruit CRBN protein. The Boc protecting group at the end of Thalidomide-4-NH-PEG1-NH-Boc can be removed under acidic conditions to participate in the synthesis of PROTAC molecules. Thalidomide-4-NH-PEG1-NH-Boc is a key intermediate in the synthesis of CRBN-based PROTAC molecules. |
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| Related Catalog |
| Molecular Formula | C22H28N4O7 |
|---|---|
| Molecular Weight | 460.48 |