Thalidomide-4-NH-PEG1-NH-Boc

Modify Date: 2025-08-25 16:06:11

Thalidomide-4-NH-PEG1-NH-Boc Structure
Thalidomide-4-NH-PEG1-NH-Boc structure
Common Name Thalidomide-4-NH-PEG1-NH-Boc
CAS Number 2154342-17-1 Molecular Weight 460.48
Density N/A Boiling Point N/A
Molecular Formula C22H28N4O7 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Thalidomide-4-NH-PEG1-NH-Boc


Thalidomide-4-NH-PEG1-NH-Boc is a Boc-modified Thalidomide (HY-14658) that acts as a Cereblon ligand to recruit CRBN protein. The Boc protecting group at the end of Thalidomide-4-NH-PEG1-NH-Boc can be removed under acidic conditions to participate in the synthesis of PROTAC molecules. Thalidomide-4-NH-PEG1-NH-Boc is a key intermediate in the synthesis of CRBN-based PROTAC molecules.

 Names

Name Thalidomide-NH-PEG1-NH-Boc

 Thalidomide-4-NH-PEG1-NH-Boc Biological Activity

Description Thalidomide-4-NH-PEG1-NH-Boc is a Boc-modified Thalidomide (HY-14658) that acts as a Cereblon ligand to recruit CRBN protein. The Boc protecting group at the end of Thalidomide-4-NH-PEG1-NH-Boc can be removed under acidic conditions to participate in the synthesis of PROTAC molecules. Thalidomide-4-NH-PEG1-NH-Boc is a key intermediate in the synthesis of CRBN-based PROTAC molecules.
Related Catalog

 Chemical & Physical Properties

Molecular Formula C22H28N4O7
Molecular Weight 460.48
The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.