64603-03-8

64603-03-8 structure
64603-03-8 structure
  • Name: AL-3138
  • Chemical Name: AL-3138
  • CAS Number: 64603-03-8
  • Molecular Formula: C20H33FO4
  • Molecular Weight: 356.47
  • Catalog: Signaling Pathways GPCR/G Protein Prostaglandin Receptor
  • Create Date: 2023-04-02 15:18:48
  • Modify Date: 2024-04-10 19:07:00
  • AL-3138 (11-Deoxy-16-fluoro PGF2α) is a prostaglandin F2 alpha (PGF2alpha) analogue that antagonises FP prostaglandin receptor-mediated inositol phosphate production[1].

Name AL-3138
Description AL-3138 (11-Deoxy-16-fluoro PGF2α) is a prostaglandin F2 alpha (PGF2alpha) analogue that antagonises FP prostaglandin receptor-mediated inositol phosphate production[1].
Related Catalog
In Vitro AL-3138 对 A7r5 细胞和 3T3 细胞的作用EC50 值分别为 72.2 nM 和 20.5 nM。此外,AL-3138 在 A7r5 细胞中对氟苯尼考的作用被确定为 Ki = 296 nM 和 Kb = 182 nM[1]。
References

[1]. Sharif NA, et al. AL-3138 antagonizes FP prostanoid receptor-mediated inositol phosphates generation: comparison with some purported FP antagonists. J Pharm Pharmacol. 2000 Dec;52(12):1529-39.   

Molecular Formula C20H33FO4
Molecular Weight 356.47
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