64603-03-8

64603-03-8 structure

64603-03-8 structure

Name: AL-3138
Chemical Name: AL-3138
CAS Number: 64603-03-8
Molecular Formula: C₂₀H₃₃FO₄
Molecular Weight: 356.47
Catalog: Signaling Pathways GPCR/G Protein Prostaglandin Receptor
Create Date: 2023-04-02 15:18:48
Modify Date: 2024-04-10 19:07:00
AL-3138 (11-Deoxy-16-fluoro PGF2α) is a prostaglandin F2 alpha (PGF2alpha) analogue that antagonises FP prostaglandin receptor-mediated inositol phosphate production[1].

Name	AL-3138

Description	AL-3138 (11-Deoxy-16-fluoro PGF2α) is a prostaglandin F2 alpha (PGF2alpha) analogue that antagonises FP prostaglandin receptor-mediated inositol phosphate production[1].
Related Catalog	Research Areas >> Endocrinology Signaling Pathways >> GPCR/G Protein >> Prostaglandin Receptor
In Vitro	AL-3138 对 A7r5 细胞和 3T3 细胞的作用EC50 值分别为 72.2 nM 和 20.5 nM。此外，AL-3138 在 A7r5 细胞中对氟苯尼考的作用被确定为 Ki = 296 nM 和 Kb = 182 nM[1]。
References	[1]. Sharif NA, et al. AL-3138 antagonizes FP prostanoid receptor-mediated inositol phosphates generation: comparison with some purported FP antagonists. J Pharm Pharmacol. 2000 Dec;52(12):1529-39.

Molecular Formula	C₂₀H₃₃FO₄
Molecular Weight	356.47