AL-3138

Modify Date: 2024-04-10 19:07:00

AL-3138 Structure
AL-3138 structure
Common Name AL-3138
CAS Number 64603-03-8 Molecular Weight 356.47
Density N/A Boiling Point N/A
Molecular Formula C20H33FO4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of AL-3138


AL-3138 (11-Deoxy-16-fluoro PGF2α) is a prostaglandin F2 alpha (PGF2alpha) analogue that antagonises FP prostaglandin receptor-mediated inositol phosphate production[1].

 Names

Name AL-3138

 AL-3138 Biological Activity

Description AL-3138 (11-Deoxy-16-fluoro PGF2α) is a prostaglandin F2 alpha (PGF2alpha) analogue that antagonises FP prostaglandin receptor-mediated inositol phosphate production[1].
Related Catalog
In Vitro AL-3138 对 A7r5 细胞和 3T3 细胞的作用EC50 值分别为 72.2 nM 和 20.5 nM。此外,AL-3138 在 A7r5 细胞中对氟苯尼考的作用被确定为 Ki = 296 nM 和 Kb = 182 nM[1]。
References

[1]. Sharif NA, et al. AL-3138 antagonizes FP prostanoid receptor-mediated inositol phosphates generation: comparison with some purported FP antagonists. J Pharm Pharmacol. 2000 Dec;52(12):1529-39.   

 Chemical & Physical Properties

Molecular Formula C20H33FO4
Molecular Weight 356.47
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