2573048-10-7
2573048-10-7 structure
- Name: BTK-IN-22
- Chemical Name: BTK-IN-22
- CAS Number: 2573048-10-7
- Molecular Formula: C26H26N6O2
- Molecular Weight: 454.52
- Catalog: Signaling Pathways Protein Tyrosine Kinase/RTK Btk
- Create Date: 2023-04-05 00:22:46
- Modify Date: 2024-04-09 00:26:58
-
BTK-IN-22 is a BTK inhibitor (IC50: 0.9 nM). BTK-IN-22 also inhibits BLX and BMX with IC50s of 1.4 and 1.2 nM respectively. BTK-IN-22 shows improved kinase selectivity compared to Ibrutinib (HY-10997)[1]
| Name | BTK-IN-22 |
|---|
| Description | BTK-IN-22 is a BTK inhibitor (IC50: 0.9 nM). BTK-IN-22 also inhibits BLX and BMX with IC50s of 1.4 and 1.2 nM respectively. BTK-IN-22 shows improved kinase selectivity compared to Ibrutinib (HY-10997)[1] |
|---|---|
| Related Catalog | |
| In Vitro | BTK-IN-23 (Compound 2) 抑制 Jeko-1 细胞中 BTK 自磷酸化，IC50 值为 109 nM[1]. Western Blot Analysis[1] Cell Line: Jeko-1 cell Concentration: 0.01, 0.1, 1, 10 μM Incubation Time: 2 h Result: Inhibited BTK autophosphorylation. |
| References |
| Molecular Formula | C26H26N6O2 |
|---|---|
| Molecular Weight | 454.52 |