2799717-96-5

2799717-96-5 structure

2799717-96-5 structure

Name: c-Myc inhibitor 9
Chemical Name: c-Myc inhibitor 9
CAS Number: 2799717-96-5
Molecular Formula: C₂₇H₃₁N₅OS
Molecular Weight: 473.63
Catalog: Signaling Pathways Apoptosis c-Myc
Create Date: 2023-04-09 19:48:30
Modify Date: 2024-04-08 12:09:30
c-Myc inhibitor 9 (compound 332) is a c-Myc inhibitor with an logEC50 of ≥6. c-Myc inhibitor 9 inhibits tumor growth in nude mouse models. c-Myc inhibitor 9 can be used for cancer research[1].

Name	c-Myc inhibitor 9

Description	c-Myc inhibitor 9 (compound 332) is a c-Myc inhibitor with an logEC50 of ≥6. c-Myc inhibitor 9 inhibits tumor growth in nude mouse models. c-Myc inhibitor 9 can be used for cancer research[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Apoptosis >> c-Myc
In Vitro	c-Myc inhibitor 9 对 Myc 具有活性，在表达 c-Myc 的 A549 细胞中，logEC50 值 ≥6[1]。
In Vivo	c-Myc inhibitor 9 (3 mg/kg；腹腔注射，每周 2 次，49 天) 有效抑制 A549 异种移植裸鼠的肿瘤生长[1]。 Animal Model: NMRI female nude mice with A549 xenografts[1] Dosage: 3 mg/kg Administration: Intraperitoneal injection; 3 mg/kg, twice a week, for 49 days Result: Reduced tumor volume.
References	[1]. Sheppard, David William, et al. Preparation of heteroaryl compounds as c-MYC mRNA translation modulators and uses thereof in the treatment of cancer. WO2022150316. 2022.

Molecular Formula	C₂₇H₃₁N₅OS
Molecular Weight	473.63