2314361-39-0
2314361-39-0 structure
- Name: Cavα2δ1&NET-IN-1
- Chemical Name: Cavα2δ1&NET-IN-1
- CAS Number: 2314361-39-0
- Molecular Formula: C23H26N4O2S
- Molecular Weight: 422.54
- Catalog: Signaling Pathways Membrane Transporter/Ion Channel Calcium Channel
- Create Date: 2023-04-04 20:05:25
- Modify Date: 2024-01-12 14:42:38
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Cavα2δ1&NET-IN-1 (Compound 59S) is a dual inhibitor of the α2δ‑1 subunit of voltage-gated calcium channels (Cavα2δ-1) and the norepinephrine transporter (NET). Cavα2δ1&NET-IN-1 inhibits Cavα2δ-1 with a Ki of 112 nM. Cavα2δ1&NET-IN-1 inhibits NET with a Ki of 383 nM and IC50 of 67 nM. Cavα2δ1&NET-IN-1 can be used for research of pain[1].
| Name | Cavα2δ1&NET-IN-1 |
|---|
| Description | Cavα2δ1&NET-IN-1 (Compound 59S) is a dual inhibitor of the α2δ‑1 subunit of voltage-gated calcium channels (Cavα2δ-1) and the norepinephrine transporter (NET). Cavα2δ1&NET-IN-1 inhibits Cavα2δ-1 with a Ki of 112 nM. Cavα2δ1&NET-IN-1 inhibits NET with a Ki of 383 nM and IC50 of 67 nM. Cavα2δ1&NET-IN-1 can be used for research of pain[1]. |
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| Related Catalog | |
| Target |
Cavα2δ1: 112 nM (Ki); NET: 383 nM (Ki), 67 nM (IC50). |
| References |
| Molecular Formula | C23H26N4O2S |
|---|---|
| Molecular Weight | 422.54 |