2446664-72-6
2446664-72-6 structure
- Name: FGFR3-IN-5
- Chemical Name: FGFR3-IN-5
- CAS Number: 2446664-72-6
- Molecular Formula: C24H24FN7O3
- Molecular Weight: 477.49
- Catalog: Signaling Pathways Protein Tyrosine Kinase/RTK FGFR
- Create Date: 2023-05-19 11:44:34
- Modify Date: 2024-04-03 11:12:36
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FGFR3-IN-5 is a potent and selective FGFR3 inhibitor with IC50 values of 3, 44, and 289 nM for FGFR3, FGFR2, and FGFR1, respectively. FGFR3-IN-5 can be used in research of cancer[1].
| Name | FGFR3-IN-5 |
|---|
| Description | FGFR3-IN-5 is a potent and selective FGFR3 inhibitor with IC50 values of 3, 44, and 289 nM for FGFR3, FGFR2, and FGFR1, respectively. FGFR3-IN-5 can be used in research of cancer[1]. |
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| Related Catalog | |
| Target |
FGFR3:3 nM (IC50) FGFR2:44 nM (IC50) FGFR1:289 nM (IC50) |
| In Vitro | FGFR3-IN-5 (compound 37; 5 mM; 1 h; HEK-293 细胞) 抑制 FGFR 磷酸化，对 FGFR3 和 FGFR1 的 IC50 值分别为8 nM 和 59 nM[1]。 |
| References |
| Molecular Formula | C24H24FN7O3 |
|---|---|
| Molecular Weight | 477.49 |