2412004-88-5

2412004-88-5 structure

Name: Livmoniplimab
Chemical Name: Livmoniplimab
CAS Number: 2412004-88-5
Molecular Formula:
Molecular Weight:
Catalog: Signaling Pathways Stem Cell/Wnt TGF-beta/Smad
Create Date: 2023-05-04 10:38:56
Modify Date: 2024-01-09 12:10:57
Livmoniplimab (ABBV-151; ARGX-115) is a potent humanized anti-LRRC32 (GARP)/TGFβ1 monoclonal antibody. Livmoniplimab blocks LRRC32-mediated activation of latent TGFβ1. Livmoniplimab has the potential for the research of cancer[1].

Name	Livmoniplimab

Description	Livmoniplimab (ABBV-151; ARGX-115) is a potent humanized anti-LRRC32 (GARP)/TGFβ1 monoclonal antibody. Livmoniplimab blocks LRRC32-mediated activation of latent TGFβ1. Livmoniplimab has the potential for the research of cancer[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Stem Cell/Wnt >> TGF-beta/Smad Signaling Pathways >> TGF-beta/Smad >> TGF-beta/Smad
References	[1]. Li A, et al. Selective targeting of GARP-LTGFβ axis in the tumor microenvironment augments PD-1 blockade via enhancing CD8+ T cell antitumor immunity. J Immunother Cancer. 2022 Sep;10(9):e005433.

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