2598242-66-9
2598242-66-9 structure
- Name: NG-497
- Chemical Name: NG-497
- CAS Number: 2598242-66-9
- Molecular Formula: C18H21NO4
- Molecular Weight: 315.36
- Catalog: Signaling Pathways Metabolic Enzyme/Protease ATGL
- Create Date: 2023-04-14 22:02:45
- Modify Date: 2024-01-02 19:13:23
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NG-497 is a selective human adipose triglyceride lipase (ATGL) inhibitor that targets the enzymatically active patatin-like domain of human ATGL. NG-497 has potential value for tumor research[1].
| Name | NG-497 |
|---|
| Description | NG-497 is a selective human adipose triglyceride lipase (ATGL) inhibitor that targets the enzymatically active patatin-like domain of human ATGL. NG-497 has potential value for tumor research[1]. |
|---|---|
| Related Catalog | |
| In Vitro | NG-497 可选择性地使人和非人灵长类动物 ATGL 失活，但不会使结构和功能相关的脂质水解酶失活，并以剂量依赖性和可逆的方式消除人类脂肪细胞的脂肪分解[1]。 NG-497(40 μM, 80 min)可以减少 HepG2 细胞的脂解依赖性呼吸，并且不会通过脱靶效应损害线粒体功能[1]。 |
| References |
| Molecular Formula | C18H21NO4 |
|---|---|
| Molecular Weight | 315.36 |