2170118-23-5

2170118-23-5 structure

2170118-23-5 structure

Name: SN38-COOH
Chemical Name: SN38-COOH
CAS Number: 2170118-23-5
Molecular Formula: C₂₆H₂₄N₂O₈
Molecular Weight: 492.48
Catalog: Research Areas Cancer
Create Date: 2023-04-19 18:56:46
Modify Date: 2024-04-06 16:46:00
SN38-COOH is used for the synthesis of antibody-drug conjugates (ADCs). SN-38 is an active metabolite of the Topoisomerase I inhibitor Irinotecan. SN-38 inhibits DNA and RNA synthesis[1][2].

Name	SN38-COOH

Description	SN38-COOH is used for the synthesis of antibody-drug conjugates (ADCs). SN-38 is an active metabolite of the Topoisomerase I inhibitor Irinotecan. SN-38 inhibits DNA and RNA synthesis[1][2].
Related Catalog	Research Areas >> Cancer
References	[1]. Wilson Lim, et al. Addressing the most neglected diseases through an open research model: The discovery of fenarimols as novel drug candidates for eumycetoma. PLoS Negl Trop Dis. 2018 Apr 26;12(4):e0006437. [2]. Wallin A, et al. Anticancer effect of SN-38 on colon cancer cell lines with different metastatic potential. Oncol Rep. 2008 Jun;19(6):1493-8.

Molecular Formula	C₂₆H₂₄N₂O₈
Molecular Weight	492.48