SN38-COOH

Modify Date: 2024-04-06 16:46:00

SN38-COOH Structure
SN38-COOH structure
Common Name SN38-COOH
CAS Number 2170118-23-5 Molecular Weight 492.48
Density N/A Boiling Point N/A
Molecular Formula C26H24N2O8 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of SN38-COOH


SN38-COOH is used for the synthesis of antibody-drug conjugates (ADCs). SN-38 is an active metabolite of the Topoisomerase I inhibitor Irinotecan. SN-38 inhibits DNA and RNA synthesis[1][2].

 Names

Name SN38-COOH

 SN38-COOH Biological Activity

Description SN38-COOH is used for the synthesis of antibody-drug conjugates (ADCs). SN-38 is an active metabolite of the Topoisomerase I inhibitor Irinotecan. SN-38 inhibits DNA and RNA synthesis[1][2].
Related Catalog
References

[1]. Wilson Lim, et al. Addressing the most neglected diseases through an open research model: The discovery of fenarimols as novel drug candidates for eumycetoma. PLoS Negl Trop Dis. 2018 Apr 26;12(4):e0006437.  

[2]. Wallin A, et al. Anticancer effect of SN-38 on colon cancer cell lines with different metastatic potential. Oncol Rep. 2008 Jun;19(6):1493-8.  

 Chemical & Physical Properties

Molecular Formula C26H24N2O8
Molecular Weight 492.48