938893-79-9

938893-79-9 structure

938893-79-9 structure

Name: Tankyrase-IN-3
Chemical Name: Tankyrase-IN-3
CAS Number: 938893-79-9
Molecular Formula: C₂₁H₂₁N₅O₄
Molecular Weight: 407.42
Catalog: Signaling Pathways Cell Cycle/DNA Damage PARP
Create Date: 2023-04-10 11:14:01
Modify Date: 2024-01-02 18:57:52
Tankyrase-IN-3 is a tankyrase 1 (TNKS1) inhibitor with an IC50 value of 22 nM. Tankyrase-IN-3 can be used for the research of cancer[1].

Name	Tankyrase-IN-3

Description	Tankyrase-IN-3 is a tankyrase 1 (TNKS1) inhibitor with an IC50 value of 22 nM. Tankyrase-IN-3 can be used for the research of cancer[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Epigenetics >> PARP Signaling Pathways >> Cell Cycle/DNA Damage >> PARP
Target	TNKS1:22 nM (IC50)
In Vitro	Tankyrase-IN-3 具有 TNKS1 抑制活性，IC50 值为 22 nM[1]。
References	[1]. Alba L Montoya, et al. Combining pharmacophore models derived from DNA-encoded chemical libraries with structure-based exploration to predict Tankyrase 1 inhibitors. Eur J Med Chem. 2023 Jan 15;246:114980.

Molecular Formula	C₂₁H₂₁N₅O₄
Molecular Weight	407.42