1571903-56-4
1571903-56-4 structure
- Name: Vabametkib
- Chemical Name: Vabametkib
- CAS Number: 1571903-56-4
- Molecular Formula: C29H34N12O
- Molecular Weight: 566.66
- Catalog: Signaling Pathways Protein Tyrosine Kinase/RTK c-Met/HGFR
- Create Date: 2023-04-05 12:27:31
- Modify Date: 2026-07-22 21:14:19
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Vabametkib is a potent inhibitor of hepatocyte growth factor receptor (HGFR). Vabametkib inhibits Hs746T cells proliferation and inhibits c-Met with an IC50 value of 7 nM. Vabametkib can be used as an antineoplastic agent[1][2].
| Name | Vabametkib |
|---|---|
| Synonyms | 1H-1,2,3-Triazolo[4,5-b]pyrazine, 1-[[(2S)-4-[5-[4-[(4-methyl-1-piperazinyl)methyl]phenyl]-2-pyrimidinyl]-2-morpholinyl]methyl]-6-(1-methyl-1H-pyrazol-4-yl) |
| Description | Vabametkib is a potent inhibitor of hepatocyte growth factor receptor (HGFR). Vabametkib inhibits Hs746T cells proliferation and inhibits c-Met with an IC50 value of 7 nM. Vabametkib can be used as an antineoplastic agent[1][2]. |
|---|---|
| Related Catalog | |
| References |
[1]. WHO Drug Informat ion - World Health Organization (WHO). |
| Molecular Formula | C29H34N12O |
|---|---|
| Molecular Weight | 566.66 |