2531244-56-9

2531244-56-9 structure

Name: BJJF078
Chemical Name: BJJF078
CAS Number: 2531244-56-9
Molecular Formula: C₂₇H₂₉N₃O₆S
Molecular Weight: 523.60
Catalog: Research Areas Inflammation/Immunology
Create Date: 2023-05-22 11:30:27
Modify Date: 2024-04-08 16:35:59
BJJF078 is an aminopiperidine derivative. BJJF078 is a potent inhibitor of recombinant human and mouse Transglutaminase enzyme (TG2) activity, IC50 values of 41 and 54 nM, respectively. BJJF078 also inhibits the close related enzyme TG1, with an IC50 of 0.16 μM. BJJF078 can be used for Multiple sclerosis (MS) research[1].

Name	BJJF078

Description	BJJF078 is an aminopiperidine derivative. BJJF078 is a potent inhibitor of recombinant human and mouse Transglutaminase enzyme (TG2) activity, IC50 values of 41 and 54 nM, respectively. BJJF078 also inhibits the close related enzyme TG1, with an IC50 of 0.16 μM. BJJF078 can be used for Multiple sclerosis (MS) research[1].
Related Catalog	Research Areas >> Inflammation/Immunology
Target	IC50: 41 nM (hTG2), 54 nM (mTG2), 0.16 μM (TG1)[1]
References	[1]. Chrobok NL, et al. Characterization of Transglutaminase 2 activity inhibitors in monocytes in vitro and their effect in a mouse model for multiple sclerosis. PLoS One. 2018 Apr 24;13(4):e0196433.

Molecular Formula	C₂₇H₂₉N₃O₆S
Molecular Weight	523.60