1628796-56-4

1628796-56-4 structure

Name: Diethyl succinate-13C4
Chemical Name: Diethyl succinate-13C4
CAS Number: 1628796-56-4
Molecular Formula: C₄₁₃C₄H₁₄O₄
Molecular Weight: 178.16
Catalog: Research Areas Metabolic Disease
Create Date: 2023-05-12 10:45:59
Modify Date: 2024-01-30 18:22:20
Diethyl succinate-13C4 is the 13C labeled Diethyl succinate[1]. Diethyl succinate (Diethyl Butanedioate) is used at physiological pH and crosses biological membranes, incorporates into cells in tissue culture and is metabolized by the TCA cycle. Diethyl succinate is known to be non-toxic and used in fragrances and flavoring[2].

Name	Diethyl succinate-13C4

Description	Diethyl succinate-13C4 is the 13C labeled Diethyl succinate[1]. Diethyl succinate (Diethyl Butanedioate) is used at physiological pH and crosses biological membranes, incorporates into cells in tissue culture and is metabolized by the TCA cycle. Diethyl succinate is known to be non-toxic and used in fragrances and flavoring[2].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Metabolic Disease
In Vitro	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [2]. Zacharias NM, et al. Real-time molecular imaging of tricarboxylic acid cycle metabolism in vivo by hyperpolarized 1-(13)C diethyl succinate. J Am Chem Soc. 2012 Jan 18;134(2):934-43.

Molecular Formula	C₄₁₃C₄H₁₄O₄
Molecular Weight	178.16