Shanghai Nianxing Industrial Co., Ltd
China
Product Name: VL285 Phenol
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Purity: 97.0%
Stocking Period: 10 Day
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1448188-69-9

1448188-69-9 structure

1448188-69-9 structure

Name: VL285 Phenol
Chemical Name: VL285 Phenol
CAS Number: 1448188-69-9
Molecular Formula: C₂₉H₃₂N₄O₅S
Molecular Weight: 548.65
Catalog: Research Areas Cancer
Create Date: 2023-04-25 14:43:19
Modify Date: 2024-01-16 11:55:29
VL285 Phenol is a VL285 analogue with Phenol group. VL285, a small molecule VHL ligand, can be served as a degrader for HaloPROTAC3 synthesis.VL285 degrades HaloTag7 fusion proteins (IC50=0.34 μM)[1].

Name	VL285 Phenol

Description	VL285 Phenol is a VL285 analogue with Phenol group. VL285, a small molecule VHL ligand, can be served as a degrader for HaloPROTAC3 synthesis.VL285 degrades HaloTag7 fusion proteins (IC50=0.34 μM)[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Others >> Others
In Vitro	VL285（100 μM；24 小时）减弱 HaloPROTAC3 诱导 GFP-HaloTag7 降解的能力[1]。
References	[1]. Buckley DL, et al. HaloPROTACS: Use of Small Molecule PROTACs to Induce Degradation of HaloTag Fusion Proteins. ACS Chem Biol. 2015 Aug 21;10(8):1831-7.

Molecular Formula	C₂₉H₃₂N₄O₅S
Molecular Weight	548.65

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