VL285 Phenol

Modify Date: 2024-01-16 11:55:29

VL285 Phenol Structure
VL285 Phenol structure
Common Name VL285 Phenol
CAS Number 1448188-69-9 Molecular Weight 548.65
Density N/A Boiling Point N/A
Molecular Formula C29H32N4O5S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of VL285 Phenol


VL285 Phenol is a VL285 analogue with Phenol group. VL285, a small molecule VHL ligand, can be served as a degrader for HaloPROTAC3 synthesis.VL285 degrades HaloTag7 fusion proteins (IC50=0.34 μM)[1].

 Names

Name VL285 Phenol

 VL285 Phenol Biological Activity

Description VL285 Phenol is a VL285 analogue with Phenol group. VL285, a small molecule VHL ligand, can be served as a degrader for HaloPROTAC3 synthesis.VL285 degrades HaloTag7 fusion proteins (IC50=0.34 μM)[1].
Related Catalog
In Vitro VL285(100 μM;24 小时)减弱 HaloPROTAC3 诱导 GFP-HaloTag7 降解的能力[1]。
References

[1]. Buckley DL, et al. HaloPROTACS: Use of Small Molecule PROTACs to Induce Degradation of HaloTag Fusion Proteins. ACS Chem Biol. 2015 Aug 21;10(8):1831-7.  

 Chemical & Physical Properties

Molecular Formula C29H32N4O5S
Molecular Weight 548.65
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