2750830-09-0

2750830-09-0 structure

Name: ARV-766
Chemical Name: ARV-766
CAS Number: 2750830-09-0
Molecular Formula: C₄₅H₅₄FN₇O₆
Molecular Weight: 807.95
Catalog: Signaling Pathways PROTAC PROTAC
Create Date: 2023-06-05 18:23:48
Modify Date: 2024-08-01 19:55:50
ARV-766 is an orally active and potent proteolysis targeting chimera (PROTAC) protein degrader. ARV-766 degrades wild-type androgen receptor (AR) but also relevant AR LBD mutants, including the most prevalent AR L702H, H875Y, and T878A mutations[1].

Name	ARV-766

Description	ARV-766 is an orally active and potent proteolysis targeting chimera (PROTAC) protein degrader. ARV-766 degrades wild-type androgen receptor (AR) but also relevant AR LBD mutants, including the most prevalent AR L702H, H875Y, and T878A mutations[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Signaling Pathways >> Others >> Androgen Receptor
References	[1]. Petrylak D P, et al. A phase 2 expansion study of ARV-766, a PROTAC androgen receptor (AR) degrader, in metastatic castration-resistant prostate cancer (mCRPC)[J]. 2023.

Molecular Formula	C₄₅H₅₄FN₇O₆
Molecular Weight	807.95