2891620-68-9

2891620-68-9 structure

2891620-68-9 structure

Name: CPD-1224
Chemical Name: CPD-1224
CAS Number: 2891620-68-9
Molecular Formula: C₄₃H₄₇ClN₈O₇S
Molecular Weight: 855.40
Catalog: Signaling Pathways Protein Tyrosine Kinase/RTK ALK
Create Date: 2023-07-23 23:22:16
Modify Date: 2024-03-14 10:51:02
CPD-1224 is an orally active derivative of ALK inhibitors to cereblon ligands. CPD-1224 targets to EML4-ALK oncogenic fusions, and degrades ALK and mutant L1196M/G1202R[1].

Name	CPD-1224

Description	CPD-1224 is an orally active derivative of ALK inhibitors to cereblon ligands. CPD-1224 targets to EML4-ALK oncogenic fusions, and degrades ALK and mutant L1196M/G1202R[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Protein Tyrosine Kinase/RTK >> ALK
References	[1]. Gao Y, et al. Catalytic Degraders Effectively Address Kinase Site Mutations in EML4-ALK Oncogenic Fusions. J Med Chem. 2023 Apr 10.

Molecular Formula	C₄₃H₄₇ClN₈O₇S
Molecular Weight	855.40