851471-44-8

851471-44-8 structure

Name: Anti-inflammatory agent 49
Chemical Name: Anti-inflammatory agent 49
CAS Number: 851471-44-8
Molecular Formula: C₂₁H₂₂N₈O₃S
Molecular Weight: 466.52
Catalog: Research Areas Inflammation/Immunology
Create Date: 2023-10-20 18:11:46
Modify Date: 2025-09-18 16:45:42
nti-inflammatory agent 49 (compound SC9) is a quite potent and selective inhibitor of Drp1-Fis1 interaction and can reduce FIS1-mediated mitochondrial dysfunction. The IC50 of SC9 inhibiting GTPase in vitro is 270 nM[1].

Name	Anti-inflammatory agent 49

Description	nti-inflammatory agent 49 (compound SC9) is a quite potent and selective inhibitor of Drp1-Fis1 interaction and can reduce FIS1-mediated mitochondrial dysfunction. The IC50 of SC9 inhibiting GTPase in vitro is 270 nM[1].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Inflammation/Immunology
Target	IC50: 270 nM (dynamin-related protein 1 ,Drp1 )[1]
References	[1]. Luis Rios, et al. Targeting an allosteric site in dynaminrelated protein 1 to inhibit Fis1-mediated mitochondrial dysfunction. Nat Commun. 2023 Jul 19;14(1):4356

Molecular Formula	C₂₁H₂₂N₈O₃S
Molecular Weight	466.52