1447933-37-0

1447933-37-0 structure

Name: Antitrypanosomal agent 14
Chemical Name: Antitrypanosomal agent 14
CAS Number: 1447933-37-0
Molecular Formula: C₁₄H₂₃N₃OS
Molecular Weight: 281.42
Catalog: Signaling Pathways PI3K/Akt/mTOR GSK-3
Create Date: 2023-10-03 12:49:52
Modify Date: 2024-01-14 11:24:18
Antitrypanosomal agent 14 (Compound 1) is a T. brucei inhibitor (EC50: 0.47 μM). Antitrypanosomal agent 14 inhibits TbGSK3 with an IC50 of 12 μM. Antitrypanosomal agent 14 can be used for the research of Human African trypanosomiasis[1].

Name	Antitrypanosomal agent 14

Description	Antitrypanosomal agent 14 (Compound 1) is a T. brucei inhibitor (EC50: 0.47 μM). Antitrypanosomal agent 14 inhibits TbGSK3 with an IC50 of 12 μM. Antitrypanosomal agent 14 can be used for the research of Human African trypanosomiasis[1].
Related Catalog	Signaling Pathways >> Stem Cell/Wnt >> GSK-3 Research Areas >> Infection Signaling Pathways >> PI3K/Akt/mTOR >> GSK-3
References	[1]. Cleghorn LAT, et al. Development of a 2,4-Diaminothiazole Series for the Treatment of Human African Trypanosomiasis Highlights the Importance of Static-Cidal Screening of Analogues. J Med Chem. 2023 Jul 13;66(13):8896-8916.

Molecular Formula	C₁₄H₂₃N₃OS
Molecular Weight	281.42