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2562351-92-0

2562351-92-0 structure

2562351-92-0 structure

Name: BTK-IN-25
Chemical Name: BTK-IN-25
CAS Number: 2562351-92-0
Molecular Formula: C₂₈H₂₇F₂N₃O₅
Molecular Weight: 523.53
Catalog: Signaling Pathways Protein Tyrosine Kinase/RTK Btk
Create Date: 2023-09-29 22:19:07
Modify Date: 2025-08-26 16:20:54
BTK-IN-25 (compound 71) is a potent inhibitor of BTK, and inhibits BTK(C481S) with an IC50 value of 0.77 nM. BTK-IN-25 inhibits BTK in DOHH2 cells with an IC50 value of 1 nM[1].

Name	BTK-IN-25

Description	BTK-IN-25 (compound 71) is a potent inhibitor of BTK, and inhibits BTK(C481S) with an IC50 value of 0.77 nM. BTK-IN-25 inhibits BTK in DOHH2 cells with an IC50 value of 1 nM[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Protein Tyrosine Kinase/RTK >> Btk
Target	IC50: 0.77 nM (BTK(C481S))
References	[1]. Tan H, et al. Substituted pyrrolo[2,3-b]pyridine and pyrazolo[3,4-b]pyridine derivatives as protein kinase inhibitors and their preparation, pharmaceutical compositions and use in the treatment of cell proliferative disorders. World Intellectual Property Organization, WO2020239124 A1. 2020-12-03.

Molecular Formula	C₂₈H₂₇F₂N₃O₅
Molecular Weight	523.53

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