BTK-IN-25

Modify Date: 2025-08-26 16:20:54

BTK-IN-25 structure	Common Name	BTK-IN-25
	CAS Number	2562351-92-0	Molecular Weight	523.53
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₈H₂₇F₂N₃O₅	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of BTK-IN-25

BTK-IN-25 (compound 71) is a potent inhibitor of BTK, and inhibits BTK(C481S) with an IC50 value of 0.77 nM. BTK-IN-25 inhibits BTK in DOHH2 cells with an IC50 value of 1 nM[1].

Name	BTK-IN-25

Description	BTK-IN-25 (compound 71) is a potent inhibitor of BTK, and inhibits BTK(C481S) with an IC50 value of 0.77 nM. BTK-IN-25 inhibits BTK in DOHH2 cells with an IC50 value of 1 nM[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Protein Tyrosine Kinase/RTK >> Btk
Target	IC50: 0.77 nM (BTK(C481S))
References	[1]. Tan H, et al. Substituted pyrrolo[2,3-b]pyridine and pyrazolo[3,4-b]pyridine derivatives as protein kinase inhibitors and their preparation, pharmaceutical compositions and use in the treatment of cell proliferative disorders. World Intellectual Property Organization, WO2020239124 A1. 2020-12-03.

Molecular Formula	C₂₈H₂₇F₂N₃O₅
Molecular Weight	523.53

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