1219811-83-2

1219811-83-2 structure

Name: CaSR antagonist-1
Chemical Name: CaSR antagonist-1
CAS Number: 1219811-83-2
Molecular Formula: C₂₉H₂₄FN₃O₂S
Molecular Weight: 497.58
Catalog: Signaling Pathways GPCR/G Protein CaSR
Create Date: 2023-10-18 16:31:43
Modify Date: 2024-03-14 12:51:47
CaSRantagonist-1 is a calcium sensing receptor (CaSR) antagonistwith an IC50 value of 50 nM. CaSRantagonist-1 can be used for the research of disorders associated with abnormalbone or mineral homeostasis such as osteoporosis[1].

Name	CaSR antagonist-1

Description	CaSRantagonist-1 is a calcium sensing receptor (CaSR) antagonistwith an IC50 value of 50 nM. CaSRantagonist-1 can be used for the research of disorders associated with abnormalbone or mineral homeostasis such as osteoporosis[1].
Related Catalog	Research Areas >> Metabolic Disease Signaling Pathways >> GPCR/G Protein >> CaSR
Target	IC50:50 nM (CaSR)[1].EC50:＞50 μM (hPXR Gene reporter assay)[1].
References	[1]. Ramanjulu JM, et al. Overcoming the Pregnane XReceptor Liability: Rational Design to Eliminate PXR-Mediated CYP Induction.ACS Med Chem Lett. 2021 Aug 10;12(9):1396-1404.

Molecular Formula	C₂₉H₂₄FN₃O₂S
Molecular Weight	497.58