745816-74-4

745816-74-4 structure

Name: (D-Arg8)-Inotocin
Chemical Name: (D-Arg8)-Inotocin
CAS Number: 745816-74-4
Molecular Formula: C₃₉H₆₈N₁₄O₁₁S₂
Molecular Weight: 973.17
Catalog: Signaling Pathways GPCR/G Protein Vasopressin Receptor
Create Date: 2023-09-29 16:24:12
Modify Date: 2024-01-11 11:44:05
(D-Arg8)-Inotocin is a potent, selective and competitive antagonist of vasopressin receptor (V1aR), with a Ki of 1.3 nM. (D-Arg8)-Inotocin shows more than 3000-fold selectivity for the human V1aR over the other three subtypes, OTR, V1bR and V2R[1].

Name	(D-Arg8)-Inotocin

Description	(D-Arg8)-Inotocin is a potent, selective and competitive antagonist of vasopressin receptor (V1aR), with a Ki of 1.3 nM. (D-Arg8)-Inotocin shows more than 3000-fold selectivity for the human V1aR over the other three subtypes, OTR, V1bR and V2R[1].
Related Catalog	Research Areas >> Cardiovascular Disease Signaling Pathways >> GPCR/G Protein >> Vasopressin Receptor
References	[1]. Giglio MGD, et, al. Development of a human vasopressin V1a-receptor antagonist from an evolutionary-related insect neuropeptide. Sci Rep. 2017 Feb 1;7:41002.

Molecular Formula	C₃₉H₆₈N₁₄O₁₁S₂
Molecular Weight	973.17