(D-Arg8)-Inotocin

Modify Date: 2024-01-11 11:44:05

(D-Arg8)-Inotocin Structure
(D-Arg8)-Inotocin structure
Common Name (D-Arg8)-Inotocin
CAS Number 745816-74-4 Molecular Weight 973.17
Density N/A Boiling Point N/A
Molecular Formula C39H68N14O11S2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of (D-Arg8)-Inotocin


(D-Arg8)-Inotocin is a potent, selective and competitive antagonist of vasopressin receptor (V1aR), with a Ki of 1.3 nM. (D-Arg8)-Inotocin shows more than 3000-fold selectivity for the human V1aR over the other three subtypes, OTR, V1bR and V2R[1].

 Names

Name (D-Arg8)-Inotocin

 (D-Arg8)-Inotocin Biological Activity

Description (D-Arg8)-Inotocin is a potent, selective and competitive antagonist of vasopressin receptor (V1aR), with a Ki of 1.3 nM. (D-Arg8)-Inotocin shows more than 3000-fold selectivity for the human V1aR over the other three subtypes, OTR, V1bR and V2R[1].
Related Catalog
References

[1]. Giglio MGD, et, al. Development of a human vasopressin V1a-receptor antagonist from an evolutionary-related insect neuropeptide. Sci Rep. 2017 Feb 1;7:41002.  

 Chemical & Physical Properties

Molecular Formula C39H68N14O11S2
Molecular Weight 973.17