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2387570-00-3

2387570-00-3 structure
2387570-00-3 structure
  • Name: DZD1516
  • Chemical Name: DZD1516
  • CAS Number: 2387570-00-3
  • Molecular Formula: C28H27F2N7O3
  • Molecular Weight: 547.56
  • Catalog: Signaling Pathways JAK/STAT Signaling EGFR
  • Create Date: 2023-10-01 03:33:59
  • Modify Date: 2024-01-04 09:53:24
  • DZD1516 is a potent and selective HER2 inhibitor (IC50=0.56 nM) with good blood-brain permeability. DZD1516 exhibits antitumor activity in CNS and subcutaneous xenograft mouse models[1].

Name DZD1516
Description DZD1516 is a potent and selective HER2 inhibitor (IC50=0.56 nM) with good blood-brain permeability. DZD1516 exhibits antitumor activity in CNS and subcutaneous xenograft mouse models[1].
Related Catalog
Target

HER2

References

[1]. Zhang J, et al. Preclinical and clinical activity of DZD1516, a full blood-brain barrier-penetrant, highly selective HER2 inhibitor. Breast Cancer Res. 2023 Jul 6;25(1):81.  

Molecular Formula C28H27F2N7O3
Molecular Weight 547.56
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