DZD1516
Modify Date: 2025-08-27 10:26:38
DZD1516 structure
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Common Name | DZD1516 | ||
|---|---|---|---|---|
| CAS Number | 2387570-00-3 | Molecular Weight | 547.56 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C28H27F2N7O3 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of DZD1516DZD1516 is a potent and selective HER2 inhibitor (IC50=0.56 nM) with good blood-brain permeability. DZD1516 exhibits antitumor activity in CNS and subcutaneous xenograft mouse models[1]. |
| Name | DZD1516 |
|---|
| Description | DZD1516 is a potent and selective HER2 inhibitor (IC50=0.56 nM) with good blood-brain permeability. DZD1516 exhibits antitumor activity in CNS and subcutaneous xenograft mouse models[1]. |
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| Related Catalog | |
| Target |
HER2 |
| References |
| Molecular Formula | C28H27F2N7O3 |
|---|---|
| Molecular Weight | 547.56 |
| InChIKey | IDQNCHCNBVCUHC-DEOSSOPVSA-N |
| SMILES | COc1cc(OC2CCN(C)CC2(F)F)c2c(Nc3ccc(Oc4ccn5ncnc5c4)c(C)c3)ncnc2c1 |