DZD1516

Modify Date: 2024-01-04 09:53:24

DZD1516 structure	Common Name	DZD1516
	CAS Number	2387570-00-3	Molecular Weight	547.56
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₈H₂₇F₂N₇O₃	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of DZD1516

DZD1516 is a potent and selective HER2 inhibitor (IC50=0.56 nM) with good blood-brain permeability. DZD1516 exhibits antitumor activity in CNS and subcutaneous xenograft mouse models[1].

Name	DZD1516

Description	DZD1516 is a potent and selective HER2 inhibitor (IC50=0.56 nM) with good blood-brain permeability. DZD1516 exhibits antitumor activity in CNS and subcutaneous xenograft mouse models[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> JAK/STAT Signaling >> EGFR Signaling Pathways >> Protein Tyrosine Kinase/RTK >> EGFR
Target	HER2
References	[1]. Zhang J, et al. Preclinical and clinical activity of DZD1516, a full blood-brain barrier-penetrant, highly selective HER2 inhibitor. Breast Cancer Res. 2023 Jul 6;25(1):81.

Molecular Formula	C₂₈H₂₇F₂N₇O₃
Molecular Weight	547.56

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Shanghai Nianxing Industrial Co., Ltd
China
Product Name: DZD1516
Price: Check
Purity: 98.0%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

DC Chemicals Limited
China
Product Name: DZD1516
Price: ￥Inquiry/100mg ￥Inquiry/250mg ￥Inquiry/1g
Purity: 98.0%
Delivery: 10 Day
Contact: Tony Cao
Email: sales@dcchemicals.com

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DZD1516

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DZD1516 Biological Activity

Chemical & Physical Properties

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.