1266548-74-6

1266548-74-6 structure

Name: Hyzetimibe
Chemical Name: Hyzetimibe
CAS Number: 1266548-74-6
Molecular Formula: C₂₅H₂₁F₂NO₃
Molecular Weight: 421.44
Catalog: Research Areas Metabolic Disease
Create Date: 2023-10-01 17:29:38
Modify Date: 2024-01-21 15:45:43
Hyzetimibe is a cholesterol absorption inhibitor. Hyzetimibe blocks the intestinal absorption of cholesterol and phytol. Hyzetimibe is well tolerated in animal models, with an LDmax 2000 mg/kg in rats and an LDmax 500 mg/kg in rhesus monkeys[1].

Name	Hyzetimibe

Description	Hyzetimibe is a cholesterol absorption inhibitor. Hyzetimibe blocks the intestinal absorption of cholesterol and phytol. Hyzetimibe is well tolerated in animal models, with an LDmax 2000 mg/kg in rats and an LDmax 500 mg/kg in rhesus monkeys[1].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Metabolic Disease
References	[1]. Ruan Z, et al. Pharmacokinetics, pharmacodynamics, safety, and tolerability of hyzetimibe (HS-25) in healthy Chinese subjects. J Clin Pharmacol. 2014 Oct;54(10):1144-52.

Molecular Formula	C₂₅H₂₁F₂NO₃
Molecular Weight	421.44